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They can include headache, dizziness, nausea or vomiting, fatigue, blurred vision, sensitivity to light or noise, balance problems, confusion, memory problems, difficulty concentrating, feeling mentally "foggy," irritability, mood swings, anxiety, depression, and sleep disturbances

Peer review Peer review information Nature Reviews Gastroenterology & Hepatology thanks Kathleen DelGiorno and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Author contributions All authors contributed to the studys conception and data interpretation