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According to a 2023 review, a compound in wild yams called gracillin possesses anti-inflammatory properties and significantly improved the skin barrier and hydration of mice with atopic dermatitis.10 Additionally, a 2017 study noted that several species of wild yams have demonstrated antimicrobial activity, leading to their use in different forms of traditional medicine as a way to treat skin infections.11 To learn more about the potentially beneficial ingredients in our picks, see each products dedicated section later on

The BK channel opener BMS-191011 was shown to suppress behavioral evidence of salicylate-induced tinnitus in mice, with local application in the inferior colliculus reversing salicylate-suppressed spontaneous activity, particularly in the frequency region corresponding to the tinnitus percept, highlighting a key site of action see in Figure 2 - (Scott et al., 2022)