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Description
Widespread rapid reductions in body size of adult salamanders in response to climate change

In the absence of GRAIL, CUL5 is neddylated, leading to the degradation of IL-2R signaling proteins such as pJAK1

Both C5a and C3a enhance vascular permeability, resulting in plasma exudation and joint swelling

Many would develop scurvy, a life-threatening vitamin C deficiency
