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Interestingly, the concentration of glucose in the medium did significantly influence the amount of formed product

[397] found a significantly increased accumulation of dysfunctional mitochondria in the fibroblasts isolated from SLOS patients under steady-state conditions compared to control cells

In general, the 3.0 and 4.5 g/d groups exhibited dramatically greater rates of DEC compared with baseline while the 1.5 g/d dosage resulted in greater resistance to fatigue on sprints 1 and 2 with more modest changes in DEC with sprints 3 -5
