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Cardiovascular Safety Heart rate increases of approximately 2-6 beats per minute have been observed with orforglipron across clinical trials, consistent with the class effect of GLP-1 receptor agonists
Gorzkiewicz and Szemraj, 2018
However, to confirm the structure of the unknown compounds, especially those for which reference materials are not available, nuclear magnetic resonance (NMR) spectrometry is recommended (Rebiere et al., 2017
