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3.2 Trends in FDA-approved drugs for Alzheimers disease The development of pharmacological treatments for AD has been a significant focus of medical research, yet current FDA-approved drugs remain limited in their ability to modify the diseases progression

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193 Interestingly, a recent study identified a GPX4- and FSP1-independent regulation of ferroptosis involving the phospholipid-modifying enzymes MBOAT1 and MBOAT2, which are regulated by sex hormones