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To gather the most current knowledge, we conducted a review of the literature using PUBMED, Google Scholar and the Cochrane Library Databases

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Chronic Diseases Influenced by ROS-Modalities of Action The ROS Sources Free radicals are generally produced as a result of the influence of external factors, such as pollution, cigarette smoke, or internally, as a result of intracellular metabolism if the antioxidant mechanisms are overwhelmed (Figure 1)

As mentioned previously, the constitutive activation of signaling molecules like kinases drives the cell cycle out of control and results in cancer