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Oral citicoline (1,600 mg/day) was given for 60 days followed by 60 days of washout, and the therapeutic cycle was repeated once
doi: 10.1002/mc.2940080309
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COMT inhibitors COMT inhibitors primarily function by inhibiting COMT, thereby increasing the concentration of L-DOPA in the brain and preventing its peripheral degradation into 3-O-methyldopa (3-OMD)
