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The goals of treatment are to reduce inflammation, eradicate infection, improve drainage and aeration of nasal and sinus mucosa, and restore mucociliary function.2 Common medical therapies for acute rhinosinusitis include antibiotics, nasal saline irrigation, decongestants, antihistamines, mucolytics, topical or systemic corticosteroids, and anti-inflammatory drugs

While, based on our previous study we would not expect significant changes to occur in the measured study outcomes 31 , future placebo-controlled randomized trials with liposomal GSH will be required to confirm the specificity of its intervention effects

Hydroxyproline incorporation assays measure increased collagen production rates, with procollagen ELISA protocols confirming enhanced synthesis at the molecular level

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