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Description
Normal and pathological NRF2 signalling in the central nervous system

the present invention solves these problems by providing BPC peptide salts and a pharmaceutical or diagnostic composition comprising a pharmaceutically or diagnostically effective amount of the salts of BPC peptides said peptides being constituted of 8 to 15 amino acids, wherein the anion of the salt is a negatively charged peptide comprising 8 amino acid residues having the general formula (I) wherein Xaa is a neutral aliphatic amino acid residue, in particular Ala, bAla, Leu, Ile, Gly, Val, Nle or Nva, Yaa is a basic amino acid residue, in particular Lys, Arg, Orn or His and Zaa is an acidic amino acid residue, in particular Glu, Asp, Aad or Apm and wherein the cation of the salt is the cation of an inorganic or organic nontoxic and pharmaceutically acceptable base

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10.1002/hep.30426 163 RazaniB.ZhangX