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Suphatase 1 and sulphatase 2 are secreted endosulphatases that remove 6- O -sulphate residues from HS and modulate HS binding to many cytokines and growth factors, including FGF1 and vascular endothelial growth factor (VEGF) 29

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Chemical conjugation of epothilone with glutathione was studied, displaying a noticeable increasing of its anticancer activity towards various tumor cells [75], however, using several chemicals as cross-linkers for orienting the reaction, and checking the progress of reaction, and extra steps for purifying the conjugate is the major challenge

Generally, the FRAP test, as a non-radical SET-based method, was promoted as having a low relation with the process of radical extinction (the HAT mechanism) occurring in lipid systems and has a low correlation with other antioxidant activity measurements