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Proc Natl Acad Sci U S A 117(8):43374346

The expression of ATGL is stimulated by various factors, including proliferator-activated receptor (PPAR) agonists, mammalian target of rapamycin complex 1 (mTORC1) inhibition, and forkhead box O 1 (FOXO1) activation [77,78,79]

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If the toenail is removed or ablated, the distal nail bed and soft tissue can grow in an elevated direction because of lack of dorsal pressure from the nail (Fig
