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Typically, you can start to feel the positive effects of the IM shot, between 24 - 72 hours post injection, dependent of current levels of B12 in the body

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Vitamin B12 and bariatric surgery After gastric bypass and sleeve gastrectomy surgery, absorption of vitamin B12 from food and oral supplements is compromised as the substance produced by the stomach which helps you to absorb the vitamin B12 is significantly reduced or even totally absent