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The elimination half-lives of chloroquine, desethylchloroquine, and bisdesethylchloroquine are all from 20 to 60 days
Simn-Snchez J, Schulte C, Bras JM, Sharma M, Gibbs JR, Berg D, et al
Small-molecule modulation of TDP-43 recruitment to stress granules prevents persistent TDP-43 accumulation in ALS/FTD
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