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Description
Evidence has shown that NNMT expression in white adipose tissue (WAT) is high in obesity-prone mice and low in obesity-resistant mice [2325] and significantly correlates with the percent fat mass in diet-induced obese mice [26]
in Regulatory Toxicology and Pharmacology confirmed the favorable safety profile of this compound across multiple evaluated parameters
Exposure of N
Signal of cysteine, which is required for glutathione synthesis (Figure 1E), was selectively depleted within TLS in injured kidneys, whereas it was uniformly distributed in healthy kidneys (Figure 1F)
