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demonstrated that a borneol-modified lipid nanoparticle nasal spray with a viscosity of 39.36 millipascal-seconds significantly increased the olfactory deposition fraction to 23.58%, showing a strong correlation with intracerebral drug delivery compared with formulations exhibiting either higher or lower viscosities (Wang et al., 2024a)

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Curr Neuropharmacol 16:13481357 Sandeep, Sahu MR, Rani L, Kharat AS, Mondal AC (2023) Could vitamins have a positive impact on the treatment of Parkinsons disease

Thus, while cellular studies indicate low toxicity and functional potential, further in vivo studies are required to assess distribution, metabolism, and clearance, as well as their long-term effects on organs and immune response (Table 3)