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Description
Any unexpected side effect, like water retention, could be a sign of contaminants triggering an off-target reaction
Nrf2: nuclear factor erythroid 2-related factor 2
For some agents, antioxidant activity may contribute to their efficacy, but therapeutic doses are frequently too low to elicit a meaningful antioxidant response
To understand this better, consider these aspects of ROS impact on skin: UV radiation as a major trigger: Sunlight generates ROS in skin cells, causing photoaging thats distinct from natural chronological aging
