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Frustratingly, some celebrities seem to have hit the headlines with trendy B12 injections, which undermines the seriousness of pernicious anaemia and the difficulties many patients have with getting the treatment they need

However, factors like aging, environmental toxins, poor diet, and stress can deplete glutathione levels, leading to a variety of health challenges

Among other things, this is due to the fact that patients with pyruvate dehydrogenase deficiency are in a way dependent on food-derived glucose, as gluconeogenesis itself is impaired in these individuals [59]

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