benefits of glutathione and selenium is involved in detoxification suppresses the selenate-induced SULTR1;1 gene expression in plants Selenium's Role in Optimizing Poultry

This is a normal and expected response, not a side effect to be concerned about

Res Vet Sci

[55], found that oral administration of NAC reduced lead (Pb)-induced cytotoxicity, genotoxicity and oxidative stress in hepatic cells

In more detail, the association between dysbiosis and insulin resistance is thought to be connected with the enhanced intestinal permeability and endotoxemia, associated with chronic low-grade inflammation, along with alterations in microbiota-derived metabolitesincluding short-chain fatty acids (SCFAs), bile acids, and branched-chain amino acids (BCAAs)which collectively may influence glucose homeostasis and energy balance [121]