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Myelin is produced by oligodendrocytes in the central nervous system (CNS) wherein a single oligodendrocyte may myelinate up to 80 axon segments [1] to facilitate axonal signaling [1] and provide metabolic support to the axon [2]

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Anderson BJ, Holford NH, Armishaw JC, Aicken R

The SARS-CoV-2 infection initiates complex human host-pathogen interactions and alters mitochondrial function with significant disruption of glycolysis/TCA cycle (Warburg effect), affecting several metabolic pathways of amino acid (AA), fatty acid (FA), nucleotide, and antioxidant synthesis 139,140