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However, the glucuronidation pathway is not upregulated by repeated exposure to APAP [71] and is a minor pathway in babies and children, as discussed above [63,64]

The answer lies in a complex interplay of factors: Individual skin sensitivity: Some people's skin is simply more reactive to the fatty acids produced by Malassezia Immune system response: Your immune system's specific reaction to Malassezia determines whether inflammation occurs Skin barrier function: A compromised skin barrier allows irritating substances to penetrate more easily Sebum composition: The specific makeup of your skin oils may provide a better or worse environment for problematic Malassezia growth Understanding this fungal component is crucial because it explains why antifungal treatments often provide relief

Storage is critical: youll keep the vial refrigerated and protected from light (see Storage guidelines above)