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233 While all methods that have moved away from individual protein purification sacrifice some control over PUREs composition, they circumvent the high cost and laborious nature of producing PURE, which are two of the main barriers to its use

Moreover, integrating ROS modulation with other strategies, such as immune checkpoint inhibitors, gene-editing technologies, and combination therapies, holds significant potential to enhance treatment efficacy and reduce disease progression

Most procedures offer minimal downtime, allowing patients to return to normal activities quickly
