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In neutrophils, NE can degrade a wide variety of architecturally and functionally important molecules, such as clotting factors and complement proteins.6 NE activity may, in part, explain the significant increase of D-dimer and pulmonary hemorrhage observed in COVID-19 patients.2 Additionally, NET-bound NE can degrade local plasminogen without generating plasmin onto fibrin, thus resulting in impaired fibrinolysis

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What to Expect Timeline: Many patients start to notice improvements within a few weeks of beginning treatment

4.8 Ferroptosis and retinal detachment Retinal detachment (RD) is a significant ophthalmological condition characterized by the separation of the retina from the underlying RPE and choroid (283)