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The same review noted that pearl powder is a beneficial source of calcium that delivers it within its natural aragonite-protein matrix which includes organic components naturally integrated with the mineral content rather than as isolated calcium carbonate

In one study, pretreatment with gadolinium chloride, a suppressor of Kupffer cells, significantly prevented APAP-mediated liver injury but not NAPQI-protein adducts, suggesting a noncritical role of NAPQI-protein adducts in APAP-related hepatotoxicity [274]

It also helps patients manage the side effects of chemotherapy

J Psychiatr Pract 21:190197 Kim NW, Song YM, Kim E, Cho HS, Cheon KA, Kim SJ, Park JY (2016) Adjunctive -lipoic acid reduces weight gain compared with placebo at 12 weeks in schizophrenic patients treated with atypical antipsychotics: a double-blind randomized placebo-controlled study