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Results were statistically analyzed using two-way ANOVA or Students t-test when appropriate
These should include: (1) Examination of these processes at different stages of the disease, (2) mechanistic studies to pinpoint signaling pathways involved in the regulation of the oxidative stress and DNA damage response markers and (3) studies addressing whether the deficits reported here can be reverted with antioxidant treatments
Cells were passaged when they reached confluency using TrypLE Select, and plated at a density of 50.000 cells/cm 2
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