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Oral Cavity Cancer in Young Patients: Evidence of an Association with HPV16
What really causes oxidative damage
Concurrently, children exhibit immature adaptive immune development, making them more susceptible to Th2 response skewing (elevated IL-4/IFN- ratio) in CD4+ T cell responses, Tregs function remains relatively underdeveloped, and B cells and follicular helper T cells demonstrate delayed or inadequate antibody production, thereby weakening immune clearance efficiency and promoting immunopathological damage (50)
Other toxic molecules are then formed, leading to tissue, cellular, and DNA damage [13, 15]
