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Data gleaned from these efforts helped shape the development of the clinical trials, testing the safety and effectiveness of treatments, typically in studies of 100-300 participants

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These can manifest as skin rashes, itching, or respiratory symptoms

649 Fer-1 attenuates ferroptosis-associated iron accumulation and lipid peroxidation, and reduces pain in mice with bone cancer, 649 suggesting that ferroptosis is a potential therapeutic target common to bone cancer pain and other types of pain
