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Description
Kelly JM, Janz DM
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Often a receptor subtype is named for a particular drug that binds selectively to it, but not other receptor subtypes for the same neurotransmitter
For example, the phenotypes of mice that lack the LepRb isoform, such as db/db mice, are very similar to the phenotypes of mice lacking leptin, such as the ob/ob mice or those lacking all isoforms of LepR, such as the db 3J /db 3J mice 26
