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Patients with type 2 diabetes, following postprandial hyperglycemia (rapid increase in blood levels of glucose) exhibit significantly increased oxidative stress markers (Ceriello et al

10.3389/fmed.2020.629413 [DOI] [PMC free article] [PubMed] [Google Scholar] 259.Vinciguerra M, Romiti S, Fattouch K, De Bellis A, Greco E

640 Similarly, the age-related increases in skeletal lipoxygenase metabolism appears to influence bone loss, where 9- and 13-HODEs are shown to suppress -catenin mediated Wnt signaling, reducing osteoblast proliferation and promoting apoptosis

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