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Bernado and Svergun, 2012

Role of non-alcoholic steatohepatitis in methotrexate-induced liver injury
Tumor cells play a pivotal role in undermining immune function

7.2 Effective composition and pharmacology Hundreds of metabolites may be identified in botanical drugs by applying the proposed mass fragmentation pathways to liquid chromatography with tandem mass spectrometry datasets, causing the toxicity of the botanical drugs to coexist with the active metabolites (Liu et al., 2012)
