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Using cultured human fibroblasts under oxidative stress conditions: Ergothioneine treatment resulted in significantly longer median telomere length after 8 weeks The percentage of short telomeres was significantly reduced across all tested concentrations The rate of telomere shortening was decreased Effects were dose-dependent at physiologically relevant concentrations Dr

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Mechanistically, we reveal that VRK2 inhibition disrupts endoplasmic reticulum (ER)-to-Golgi trafficking of SLC7A11, consequently diminishing GSH biosynthesis and predisposing PC cells to ferroptosis

JAMA Dermatol 152(9):10511052 Balkrishnan R, McMichael AJ, Camacho FT, Saltzberg F, Housman TS, Grummer S et al (2003) Development and validation of a health-related quality of life instrument for women with melasma