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Serine 1177 is located on the C-terminal reductase domain and when phosphorylated, enhances eNOS activity by facilitating electron flow from NADPH to the heme domain, contributing to NO production (Fulton et al., 1999
Small studies suggest that very little, if any, injectable semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound) passes into breast milk
Philos Trans R Soc Lond B Biol Sci (2005) 360(1460):156370
