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demonstrated that increased TMAO levels were a strong predictor of mortality in patients with HF with reduced ejection fraction, but not in those with preserved ejection fraction, over a mean follow-up of 9.7 years

Wakatsuki, T., Schwab, B., Thompson, N

The other amino acid in the gel, L-ornithine, doesnt have much research on it as a topical treatment, but it does appear to have some potential as a stress hormone reducer (for cortisol, specifically) when supplemented orally.50 But, as mentioned with damiana, more research is needed

137 Randomized controlled trials are needed to formally evaluate this approach in the context of pancreatic cancer