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Description
Calcium signaling stimulates translation of hif-alpha during hypoxia
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More recently, a study conducted in human colon carcinoma HCT116 cells showed that lithocholic acid (LCA), a secondary bile acid, stimulates IL-8 expression and induces endothelial cell proliferation and tube like formation in the tumour microenvironment, providing the strong evidence for LCA as a tumour promoter in CRC (126)
Biochemistry (2005) 44:8326
