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In 2022, Elsawy and his research team published a randomised clinical trial which included a comparison of the effects of local anaesthetic injection against botulinum toxin injection for piriformis syndrome

doi: 10.1158/0008-5472.CAN-17-1744 [DOI] [PMC free article] [PubMed] [Google Scholar] 116.Abu-Rustum NR, Yashar CM, Bradley K, et al

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Besides, HO-1 improved cardiovascular function by regulating cellular signaling pathways and promoting angiogenesis, etc (Table 2)