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This degradation is irreversible and occurs without visible changes the solution remains clear, but bioactivity drops by 4060% after overnight ambient exposure
after reconstitution, refrigerate at 28 C (35.646.4 F) , protect from light, and do not freeze the mixed solution

As peer-reviewed Phase 3 results publish, this guide is updated with the confirmed figures

The remaining 3 studies, scored eight and nine, indicating high-quality studies with low risk of bias (Table 5)
