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Interestingly, the mammalian HNF4 receptors, whose LBDs share 33% identity with the NHR-49 LBD, can bind to several saturated and monounsaturated fatty acids, including stearic and oleic acid [30,31]

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In addition, it was found that in certain individuals with low serum LDL levels there was an association with the inheritance of nonsense mutations in the PCSK9 gene which result in loss of PCSK9 activity

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"Intestinal microbiota metabolism of L-carnitine promotes atherosclerosis." Nat Med 2013;19:576-85

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For the hepatocellular carcinoma patients, the goal would be to avoid recurrent HCV after transplantation

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