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Results demonstrated that GHK treatment reduced inflammatory cell infiltration, improved collagen deposition, and balanced MMP-9/TIMP-1 levels
Amino Acids (2000) 18:116
27 Subsequent structural optimization of 4 led to the identification of JBSNF-000265 ( 5 ) with an IC 50 value of 0.58 0.07 M, displaying a 3-fold improvement in activity with a favorable pharmacokinetic profile
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