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Description
doi: 10.1016/j.micpath.2021.105216 [DOI] [PubMed] [Google Scholar] 256
Dapagliflozin, which functions primarily by blocking glucose reabsorption in the proximal tubule by targeting sodium-glucose cotransporter 2 (SGLT2), is a hypoglycemic agent used in the clinic to treat diabetes
Based on the Trx1 redox status, this modification can lead to either activation or inactivation of caspase3 [133, 135]
Their mechanisms of these drugs, which include inhibiting microtubule formation or inducing DNA strand breaks, have been intensively investigated
