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Normally, the anterior pituitary secretes thyroid-stimulating hormone (TSH) in response to hypothalamic thyrotropin-releasing hormone (TRH), stimulating the thyroid to release approximately 20% triiodothyronine (T3) and 80% thyroxine (T4) (Fig

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I typically apply them in a layered approach sometimes mixing a few drops of each into my favorite serum or moisturizer