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Description
Studies have found that inhibiting KGDD activity due to mutations in IDH1/2, FH, or SDH increases sensitivity to DNA damaging agents, and the mechanisms described are due to changes in methylation (Inoue et al., 2016
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Acetylcholine, in particular, is highly vulnerable to this neuroinflammatory state
MR leverages genetic variation found in SNPs as instrumental variables (IVs) within observational contexts
