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Antioxidant supplements hold significant potential in mitigating ROS-mediated cellular and tissue damage, either by directly neutralizing free radicals, as seen with vitamins C and E, or by supporting enzymatic defense systems such as superoxide dismutase and catalase, which actively scavenge free radicals (Poljsak et al., 2013

Studies provide evidence that BIM alternative splicing molecules play a key role in drug resistance [66]

Patients will require ICU admission when they have signs of CNS toxicity, do not tolerate fluid therapy, or have serum concentrations more than 2 mmol/L, which may result in rapid deterioration