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Neurophysiological, nerve imaging and other techniques to assess chemotherapy-induced peripheral neurotoxicity in the clinical and research settings

If side effects at 1.7 mg are significant, many providers recommend staying at this dose for an additional 4 weeks before attempting the final escalation to 2.4 mg

FOXO1 respectively inhibits and enhances eNOS and inducible-NOS (iNOS), contributing to pro-atherogenic effects, as confirmed by the reduced progression of atherosclerosis in FOXO1-deleted mouse models [71, 72]

doi: 10.1146/annurev.phyto.050908.135202 71 WangS
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