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Moreover, it has been also shown that ascorbic acid in skin keratinocytes affects intracellular signaling through protein kinase C activation [71], which additionally activates Nrf2

doi: 10.1016/S2468-1253(20)30331-9

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Impact of Rivaroxaban on apoptotic and inflammatory markers Figure 3 reveals that testicular IR dramatically increased apoptotic markers, with BAX increasing by 271% and NFB increasing by 285.7% while BCL2 decreased by 65.9% compared to normal controls
