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Dietary carnitine is taken up from the intestinal lumen into the enterocyte by an active transport mechanism, but it passes across the serosal membrane into the circulation by simple diffusion

In this form, glutathione can be transported more effectively across the cell membrane

To cope with the elevated oxidative stress they generate, cancer cells enhance their antioxidant capacity, largely through sustained activation of the transcription factor NRF2 often driven by mutations in its negative regulator KEAP1

It may encourage the melanocytes to switch from producing the darker eumelanin to the lighter pheomelanin