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doi: 10.1016/j.lfs.2021.120274 27 EltayebKAlfieriRFumarolaCBonelliMGalettiMCavazzoniAet al
Yue Y, Shen P, Xu Y, Park Y

reported binucleargold(I) complex with mixed bridging diphosphine and bis( N -heterocyclic carbene) ligands that inhibited self-renewal ability in HeLa and U-87 MG human glioblastoma cells in vivo with 79% tumor volume inhibition in nude mice bearing HeLa xenografts
It is also the pathway that drives IGF-1 LR3's insulin-like glucose-lowering effect the same mechanism that creates hypoglycemia risk
