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In HCC, hypoxic tumor-derived exosomal miR-1290 promotes the polarization of M2 macrophages, triggers apoptosis in CD8+ T cells, and enhances EMT in HCC cells
If it is very high, it is usually caused by certain pathologies or functional problems related to defects in vitamin B12 uptake, leading to over-uptake and even over-release
[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Herve JC, Derangeon M, Sarrouilhe D, Bourmeyster N
