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However, in contrast to these preclinical data using parenteral drug administration, no differences were found in the hysteresis curves between lisdexamfetamine and D-amphetamine in the present study using oral drug administration, further supporting the similarity of the two substances when used orally in humans

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Methylation levels of SFRP1 , SFRP2 , SDC2 , and PRIMA1 were determined using a MethyLight assay after cfDNA isolation and bisulfite conversion of samples ( SOX21 gene promoter methylation, serving as a fecal-based noninvasive biomarker for early diagnosis of colorectal cancer (Moradi et al., 2021)