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Experimental evidence includes: GPX4-knockout mice show 3-fold larger infarcts with lipid peroxide accumulation in high-OXPHOS regions, while ferroptosis inhibitors (e.g., ferrostatin-1) reduce neuronal loss by 60% in MCAO models [163, 165]
The scar will progressively flatten and fade over 12 months
Upregulation of melanin biosynthesis or increase in the number either of normal or of atypical oral mucosal melanocytes may bring about oral mucosal melanin hyperpigmentation
