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Description
Enrichment values were calculated using the following equation: Enrichment value = (k/m)/((n-k)/(N-m)), Where m = number of metabolites in the pathway
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Mortality benefits correlated with normalization of multiple systems: Circadian melatonin rhythms restored Carbohydrate metabolism improved Lipid profiles normalized Immune function enhanced Animal studies demonstrated lifespan extension across multiple species, with epithalamin increasing mean lifespan up to 41% in rodent models [11]
Thus, a deficiency in both B9 and B12 may elevate Hcy levels and increase the risk of AD
